Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
Code | Size | Price |
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TAR-T39216-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T39216-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized conjugate that functions as an E3 ligase ligand-linker. It includes the cereblon ligand derived from Thalidomide and a linker. This compound, Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc, is employed in the synthesis of PROTAC BET degraders (From patent WO2017180417A1 compound s7).
CAS:
1799711-31-1
Molecular Weight:
634.683
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)NCCCOCCOCCOCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
References
Shaomeng Wang, et al. Bet protein degraders. WO2017180417A1.