(S,R,S)-AHPC-C6-NH2 hydrochloride
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
(S,R,S)-AHPC-C6-NH2 hydrochloride (also known as VH032-C6-NH2 hydrochloride) is a synthetic E3 ligase ligand-linker conjugate. It combines the VH032-based VHL ligand with a linker designed for AKT PROTAC degrader applications. (S,R,S)-AHPC-C6-NH2 hydrochloride also referred to as XF038-161A or example 6, was isolated from patent WO2019173516A1.
CAS:
2360522-76-3
Molecular Weight:
594.21
Purity:
0.98
SMILES:
Cl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN)C(C)(C)C)cc1 |@@:34|
References
Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.