TLR7/8 agonist 4 hydroxy-PEG10-acid
| Code | Size | Price |
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| TAR-T39968-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T39968-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a potent activator of TLR7/8. The TLR7/8 agonist 4 is linked to hydroxy-PEG10-acid, the ADC linker, via a cleavable bond. Overall, it demonstrates promising pharmaceutical potential in the context of ADC-based therapeutics.
CAS:
2388520-17-8
Molecular Weight:
837.025
Purity:
0.98
SMILES:
CCCCc1nc2c(N)nc3ccc(cc3c2[nH]1)N1CCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)CC1
References
Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.