Dimethyl-F-OICR-9429-COOH

TargetMol
Product Code: TAR-T39978
Supplier: TargetMol
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TAR-T39978-100mg100mgEnquire
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TAR-T39978-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Dimethyl-F-OICR-9429-COOH, a ligand for WD40 repeat domain protein 5 (WDR5), is isolated from patent WO2019246570A1 intermediate 19. This compound is utilized as a key component in the synthesis of PROTACs.
CAS:
2407458-49-3
Molecular Weight:
546.523
Purity:
0.98
SMILES:
C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(O)=O

References

Jin J, et, al. Wd40 repeat domain protein 5 (wdr5) degradation/disruption compounds and methods of use. WO2019246570A1.