Pomalidomide-amino-PEG5-NH2 hydrochloride
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Pomalidomide-amino-PEG5-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound combines a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.
CAS:
2421217-05-0
Molecular Weight:
587.02
Purity:
0.98
SMILES:
Cl.NCCOCCOCCOCCOCCOCC(=O)Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
References
Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.