Thalidomide-5-propargyne-NH2 hydrochloride
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TAR-T40151-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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TAR-T40151-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
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Further Information
Bioactivity:
Thalidomide-5-propargyne-NH2 hydrochloride is a cereblon ligand derived from Thalidomide that is utilized in the recruitment of CRBN protein. It can be linked to the protein ligand through a linker to produce PROTACs, which are compounds used for protein degradation.
CAS:
2490402-62-3
Molecular Weight:
347.753
Purity:
0.98
SMILES:
Cl.NCC#Cc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1
References
Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-994.