SHP2 protein degrader-1

TargetMol
Product Code: TAR-T40250
Supplier: TargetMol
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TAR-T40250-100mg100mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
SHP2 protein degrader-1 is a highly efficient allosteric inhibitor targeting SHP2. It effectively induces degradation of SHP2 protein, resulting in cell apoptosis. This compound shows promising potential for studying diseases associated with SHP2.
CAS:
2624181-69-5
Molecular Weight:
908.84
Purity:
0.98
SMILES:
CC1(CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl)NCc1cn(CCOCCOCCOCCOCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)nn1

References

Zheng M, et al. Novel PROTACs for degradation of SHP2 protein. Bioorg Chem. 2021;110:104788.