TargetMol

Thalidomide-O-C8-NH2 hydrochloride

Product Code:
 
TAR-T40261
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T40261-100mg100mgEnquire
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TAR-T40261-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Thalidomide-O-C8-NH2 hydrochloride is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide, as well as a linker employed in PROTAC technology.
CAS:
2636798-38-2
Molecular Weight:
437.92
Purity:
0.98
SMILES:
Cl.NCCCCCCCCOc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

References

Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.