RO2959 monohydrochloride
| Code | Size | Price |
|---|
| TAR-T62940-100mg | 100mg | £1,235.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
RO2959 monohydrochloride is a potent, selective inhibitor of CRAC channels (IC50: 402 nM) and a potent blocker of Orai1/Stim1 channel-mediated calcium store entry (SOCE) (IC50: 25 nM). A potent inhibitor of human IL-2 production, effectively blocking T cell receptor-triggered gene expression and T cell functional pathways.
CAS:
2309172-44-7
Molecular Weight:
463.93
Purity:
0.98
SMILES:
Cl.O=C(NC1=NC=C(N=C1)C2=C(C)CCN(C3=NC=C(S3)C)C2)C=4C(F)=CC=CC4F