Acv tripeptide
| Code | Size | Price |
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| TAR-TP2366-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TP2366-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Acv tripeptide is a crucial precursor in penicillin and cephalosporin biosyntheses.
CAS:
32467-88-2
Molecular Weight:
363.43
Purity:
0.98
SMILES:
[C@H](C(N[C@H]([C@H](C)C)C(O)=O)=O)(NC(CCC[C@@H](C(O)=O)N)=O)CS
References
Tamanaha E, Zhang B, Guo Y, Chang WC, Barr EW, Xing G, St Clair J, Ye S, Neese F, Bollinger JM Jr, Krebs C. Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase. J Am Chem Soc. 2016 Jul 20;138(28):8862-74. doi: 10.1021/jacs.6b04065. Epub 2016 Jul 5. PubMed PMID: 27193226; PubMed Central PMCID: PMC4956533.
Tahlan K, Moore MA, Jensen SE. ?-(L-?-aminoadipyl)-L-cysteinyl-D-valine synthetase (ACVS): discovery and perspectives. J Ind Microbiol Biotechnol. 2017 May;44(4-5):517-524. doi: 10.1007/s10295-016-1850-7. Epub 2016 Oct 20. Review. PubMed PMID: 27766439.
McNeill LA, Brown TJN, Sami M, Clifton IJ, Burzlaff NI, Claridge TDW, Adlington RM, Baldwin JE, Rutledge PJ, Schofield CJ. Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases. Chemistry. 2017 Sep 18;23(52):12815-12824. doi: 10.1002/chem.201701592. Epub 2017 Aug 21. PubMed PMID: 28703303; PubMed Central PMCID: PMC5637899.
Diez-Torrubia A, Cabrera S, de Castro S, Garc?a-Aparicio C, Mulder G, De Meester I, Camarasa MJ, Balzarini J, Vel?zquez S. Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzyme. Eur J Med Chem. 2013;70:456-68. doi: 10.1016/j.ejmech.2013.10.001. Epub 2013 Oct 9. PubMed PMID: 24185376.