Dynole 2-24
| Code | Size | Price |
|---|
| TAR-T61488-200mg | 200mg | £1,283.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 uM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 uM). Dynole 2 24 also shows 4.4-fold selectivity for dynamin I. Dynole 2 24 is active in-cell inhibitor of clathrin-mediated endocytosis [1]. CME: Clathrin mediated endocytosis
CAS:
1416313-72-8
Molecular Weight:
371.613
Purity:
0.98
SMILES:
CCCCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12