(Rac)-Tavapadon
| Code | Size | Price |
|---|
| TAR-T61778-200mg | 200mg | £1,144.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
(Rac)-Tavapadon ((Rac)-PF-06649751) is a highly potent and selective noncatechol dopamine D1 receptor agonist, demonstrating robust agonistic activity in the GS activation assay (GS-cAMP, EC 50 =0.8 nM) and moderate agonistic activity in the β-arrestin2 recruitment assay (β-arrestin2, EC 50 =68 nM). This compound exhibits antiparkinsonian properties, as identified in previous research [1].
CAS:
1643462-64-9
Formula:
C19H16F3N3O3
Molecular Weight:
391.34
Purity:
0.98
SMILES:
O=C1NC(=O)N(C(C=2C=CC(OC3=NC=CC=C3C(F)(F)F)=CC2C)=C1C)C