Sodium taurocholate
| Code | Size | Price |
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| TAR-TWA2417-200mg | 200mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
CAS:
145-42-6
Molecular Weight:
538.69
Purity:
0.9836
SMILES:
[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
References
Khatun, Z., Nurunnabi, M., Cho, K., Byun, Y., Bae, Y., & Lee, Y. (2014). Oral absorption mechanism and anti-angiogenesis effect of taurocholic acid-linked heparin-docetaxel conjugates.?Journal Of Controlled Release,?177, 64-73. doi: 10.1016/j.jconrel.2013.12.034
Mathavan, S., Mikov, M., Golocorbin-Kon, S., & Al-Salami, H. (2017). Diabetes development increased concentrations of the conjugated bile acid, taurocholic acid in serum, while treatment with microencapsulated-taurocholic acid exerted no hypoglycaemic effects.?European Journal Of Pharmaceutical Sciences,?106, 1-9. doi: 10.12016/j.ejps.2017.05.041