APE1-IN-1
| Code | Size | Price |
|---|
| TAR-T61487-500mg | 500mg | £1,674.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
APE1-IN-1 is a highly potent inhibitor of apurinic/apyrimidinic (AP) endonuclease 1 (APE1), which efficiently crosses the blood-brain barrier (BBB). With an IC50 value of 2 uM, APE1-IN-1 enhances the cytotoxicity of cancer cells when combined with alkylating agents such as Methylmethane sulfonate and Temozolomide [1].
CAS:
524708-03-0
Molecular Weight:
371.52
Purity:
0.98
SMILES:
O=C(NC=1SC2=C(C1C3=NC=4C=CC=CC4S3)CCN(C2)C(C)C)C