LY487379
| Code | Size | Price |
|---|
| TAR-T62756-500mg | 500mg | £1,225.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). lY487379 enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 uM) and mGlu3 receptors (EC50>10 uM). lY487379 induces cognitive flexibility and induces behavioural inhibition in a rat model. LY487379 can be used to study schizophrenia.
CAS:
353231-17-1
Formula:
C21H19F3N2O4S
Molecular Weight:
452.45
Purity:
0.98
SMILES:
COc1ccccc1Oc1ccc(cc1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F