Tivozanib hydrochloride hydrate
| Code | Size | Price |
|---|
| TAR-T63505-500mg | 500mg | £1,042.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hydrate inhibits angiogenesis and vascular permeability in tumor tissue and has antitumor effects that have potential for investigation in metastatic renal cell carcinoma (RCC).
CAS:
682745-41-1
Molecular Weight:
509.34
Purity:
0.98
SMILES:
O.Cl.COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC