SPTA1 monoclonal antibody, clone AF10

Abnova Corporation
Product Code: MAB2515
Product Group: Primary Antibodies
CodeSizePrice
MAB2515-100ug100 ug£709.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: 2 IgG1
Antibody Clonality: Monoclonal
Antibody Clone: AF10
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Description:
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
Gene ID:
6708
Gene Name:
SPTA1
Immunogen:
Native purified human SPTA1.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native SPTA1.
Quality Control Testing:
Antibody Reactive Against Native Purified Protein.
Recommend Dilutions:
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
Specificity:
This antibody is specific to the 240kD erythroid alpha-spectrin. Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific to erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Monoclonal antibody to erythroid alpha-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Storage Buffer:
In PBS (1% BSA, 0.09% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/8641337