SPTB monoclonal antibody, clone DB2

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Abnova Corporation
Product Code: MAB2516
Product Group: Primary Antibodies
CodeSizePrice
MAB2516-100ug100 ug£709.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: 2 IgG1
Antibody Clonality: Monoclonal
Antibody Clone: DB2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

Documents

Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Description:
spectrin, beta, erythrocytic
Gene ID:
6710
Gene Name:
SPTB
Immunogen:
Native purified human SPTB.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native SPTB.
Quality Control Testing:
Antibody Reactive Against Native Purified Protein.
Recommend Dilutions:
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
Specificity:
This antibody is specific to the 220kD human erythroid beta-spectrin. The protein is also present in the membranes of human skeletal muscle cells. Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific to erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Monoclonal antibody to erythroid beta-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Storage Buffer:
In PBS (1% BSA, 0.09% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/8641337
  • http://www.ncbi.nlm.nih.gov/pubmed/10677859