CD46 monoclonal antibody, clone MEM-258 (FITC)

Abnova Corporation
Product Code: MAB4441
Product Group: Primary Antibodies
CodeSizePrice
MAB4441-100Reactions100 Reactions£384.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: MEM-258
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Further Information

Antigen Target Species:
Human
Conjugate Tag:
FITC
Form:
Liquid
Gene Alias:
MCP|MGC26544|MIC10|TLX|TRA2.10
Gene Description:
CD46 molecule, complement regulatory protein
Gene ID:
4179
Gene Name:
CD46
Immunogen:
Native purified CD46 from human T cell line HPB-ALL.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native CD46.
Recommend Dilutions:
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
Specificity:
This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 KDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.
Storage Buffer:
In PBS (0.2% BSA, 0.09% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/14566335
  • http://www.ncbi.nlm.nih.gov/pubmed/16200405
  • http://www.ncbi.nlm.nih.gov/pubmed/17116876