FAS monoclonal antibody, clone LT95 (FITC)

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Abnova Corporation
Product Code: MAB4471
Product Group: Primary Antibodies
CodeSizePrice
MAB4471-100Reactions100 Reactions£384.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: LT95
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Documents

Further Information

Antigen Target Species:
Human
Conjugate Tag:
FITC
Form:
Liquid
Gene Alias:
ALPS1A|APO-1|APT1|CD95|FAS1|FASTM|TNFRSF6
Gene Description:
Fas (TNF receptor superfamily, member 6)
Gene ID:
355
Gene Name:
FAS
Immunogen:
Native purified FAS from human T cell lymphoma cell line HUT-78.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native FAS.
Recommend Dilutions:
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
Specificity:
This antibody reacts with CD95 (Fas/APO-1), a 46 KDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells.
It seems that This antibody does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.
Storage Buffer:
In PBS (0.2% BSA, 0.09% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/15941911
  • http://www.ncbi.nlm.nih.gov/pubmed/18078929
  • http://www.ncbi.nlm.nih.gov/pubmed/15757891