CD44 monoclonal antibody, clone DF 1485
| Code | Size | Price |
|---|
| MAB5315-1mL | 1 mL | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: 2 IgG1
Antibody Clonality: Monoclonal
Antibody Clone: DF 1485
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Storage:
Store at 4°C.
Documents
Further Information
Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
CDW44|CSPG8|ECMR-III|HCELL|IN|LHR|MC56|MDU2|MDU3|MGC10468|MIC4|MUTCH-I|Pgp1
Gene Description:
CD44 molecule (Indian blood group)
Gene ID:
960
Gene Name:
CD44
Immunogen:
CD44 antigen (PGp-1) purified from lymphocyte membrane.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native CD44.
Recommend Dilutions:
Immunohistochemistry (1:5-1:10)
The optimal working dilution should be determined by the end user.
The optimal working dilution should be determined by the end user.
Specificity:
HCAM, CD44 is a transmembrane glycoprotein which is expressed by lymphocytes and several normal epithelial cells. The CD44 molecule is involved in lymphocyte homing, T-lymphocyte actvitation, interaction with hyaluronic acid and may act as an adhesion molecule. Standard CD 44 (CD44s) is composed of the products of exons 1-5 a less favourable prognosis in gastrointestinal cancers, the loss of CD44s expression predicts unfavourable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinomas and neuroblastomas. In immunoblotting this antibody reacts with a glycoprotein isolated from hemopoietic cells and epithelials cells with a respective molecular weight of 29-37 and 51 kD.
Storage Buffer:
In antibody solution (0.09% sodium azide).
References
- https://www.ncbi.nlm.nih.gov/pubmed/30214726