MPO monoclonal antibody, clone 2C7

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Abnova Corporation
Product Code: MAB5342
Product Group: Primary Antibodies
CodeSizePrice
MAB5342-200ug200 ug£825.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: 2 IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 2C7
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Documents

Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Description:
myeloperoxidase
Gene ID:
4353
Gene Name:
MPO
Immunogen:
Human MPO.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against MPO.
Recommend Dilutions:
Immunohistochemistry (Frozen sections) (1:1000-1: 5000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Flow Cytometry (1:50-1:100)
The optimal working dilution should be determined by the end user.
Specificity:
This antibody recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. MON 8074 recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. This antibody also recognizes recombinant MPO in Western blots and weakly in ELISA. This antibody may be of value in the study of myeloid cells and myeloid leukaemias by flow cytometry following cell permeablisation.
Storage Buffer:
In PBS (0.09% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/?term=26718340
  • https://www.ncbi.nlm.nih.gov/pubmed/33496751