CD14 monoclonal antibody, clone biG 2 (RoMo-1)

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Abnova Corporation
Product Code: MAB5656
Product Group: Primary Antibodies
CodeSizePrice
MAB5656-100ug100 ug£384.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: biG 2 (RoMo-1)
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunoprecipitation (IP)
Storage:
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

Documents

Further Information

Antigen Target Species:
Human
Form:
Lyophilized
Gene Description:
CD14 molecule
Gene ID:
929
Gene Name:
CD14
Immunogen:
Native from human monocytes.
Product Description:
Mouse monoclonal antibody raised against native CD14.
Recommend Dilutions:
Flow Cytometry (1:5000)
The optimal working dilution should be determined by the end user.
Specificity:
biG 2 (RoMo-1) represents an excellent marker for CD14. CD14 has been shown to be involved in the LPS-induced cell activation. This antigen is present as a membrane bound form and as soluble antigen, both involved in cell stimulation by LPS. The plasma protein LBP plays an important role in this LPS-CD14 mediated cell activation. Monocytes and PMN are activated by the LBP-LPS complex via membrane CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin.
Storage Buffer:
Lyophilized from PBS

References

  • http://www.ncbi.nlm.nih.gov/pubmed/12185283
  • http://www.ncbi.nlm.nih.gov/pubmed/9535844