Abnova Corporation

CD14 monoclonal antibody, clone biG 7

Product Code:
 
MAB5658
Product Group:
 
Primary Antibodies
Supplier:
 
Abnova Corporation
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
biG 7
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Western Blot (WB)
Storage:
 
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
 

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CodeSizePrice
MAB5658-100ug100 ug£384.00
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Further Information

Antigen Target Species:
Human
Form:
Lyophilized
Gene Description:
CD14 molecule
Gene ID:
929
Gene Name:
CD14
Immunogen:
Monocytes and immunoaffinity purified soluble human CD14.
Product Description:
Mouse monoclonal antibody raised against CD14.
Recommend Dilutions:
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
Specificity:
biG 7 represents an excellent marker for CD14. CD14 has been shown to be involved in the LPS-induced cell activation. This antigen is present as a membrane bound form and as soluble antigen, both involved in cell stimulation by LPS. The plasma protein LBP plays an important role in this LPS-CD14 mediated cell activation. Monocytes and PMN are activated by the LBP-LPS complex via membrane CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin.
Storage Buffer:
Lyophilized from PBS

References

  • http://www.ncbi.nlm.nih.gov/pubmed/8612616
  • http://www.ncbi.nlm.nih.gov/pubmed/9030727