LBP monoclonal antibody, clone biG 42
| Code | Size | Price |
|---|
| MAB5661-100ug | 100 ug | £384.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: biG 42
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
Documents
Further Information
Antigen Target Species:
Human
Form:
Lyophilized
Gene Alias:
MGC22233
Gene Description:
lipopolysaccharide binding protein
Gene ID:
3929
Gene Name:
LBP
Immunogen:
Recombinant protein corresponding to human LBP.
Product Description:
Mouse monoclonal antibody raised against recombinant LBP.
Recommend Dilutions:
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
The optimal working dilution should be determined by the end user.
Specificity:
LPS binding protein (LBP) is an approximately 60 KDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on mononuclear phagocytes, leading to a 100-1,000-fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negative cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these cells. LBP was demonstrated to protect mice from septic shock caused by LPS or gram negative bacteria.
Storage Buffer:
Lyophilized from PBS
References
- http://www.ncbi.nlm.nih.gov/pubmed/15206917