NOTCH1 polyclonal antibody

Abnova Corporation
Product Code: PAB10291
Product Group: Primary Antibodies
CodeSizePrice
PAB10291-200uL200 uL£709.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
TAN1|hN1
Gene Description:
Notch homolog 1, translocation-associated (Drosophila)
Gene ID:
4851
Gene Name:
NOTCH1
Immunogen:
A synthetic peptide corresponding to N-terminus the cleaved N intracellular domain (NICD) of human NOTCH1.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.
Protein Accession:
P46531 (human)
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Dilutions:
Sandwich ELISA (1:20000-1:60000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.
Specificity:
This antiserum is directed against human NOTCH 1. Only the cleaved intracellular (activated) form (NICD) is detected. No reactivity is detected against mouse N2, N3 or N4. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form.
Storage Buffer:
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.1% sodium azide)

References

  • http://www.ncbi.nlm.nih.gov/pubmed/11187898
  • http://www.ncbi.nlm.nih.gov/pubmed/12668592