NOTCH2 polyclonal antibody

Product Code: PAB10293

Code	Size	Price

PAB10293-200uL

200 uL

£709.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit

Antibody Clonality: Polyclonal

Regulatory Status: RUO

Applications:

Enzyme-Linked Immunosorbent Assay (ELISA)
Immunohistochemistry (IHC)
Western Blot (WB)

Storage:

Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Documents

Supplier External Link

Further Information

Antigen Target Species:

Human

Form:

Liquid

Gene Alias:

AGS2|hN2

Gene Description:

Notch homolog 2 (Drosophila)

Gene ID:

4853

Gene Name:

NOTCH2

Immunogen:

A synthetic peptide corresponding to N-terminus the cleaved N intracellular domain (NICD) of human NOTCH2.

Note:

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Product Description:

Rabbit polyclonal antibody raised against synthetic peptide of NOTCH2.

Protein Accession:

Q04721(human);O35516(mouse);Q9QW30(rat);OMIMref:600275

Quality Control Testing:

Antibody Reactive Against Synthetic Peptide.

Recommend Dilutions:

Sandwich ELISA (1:30000-1:90000)
The optimal working dilution should be determined by the end user.

Specificity:

This antiserum is directed against human NOTCH 2. Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2. Only one amino acid difference (conservative) occurs in mouse and rat. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form.

Storage Buffer:

In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01% sodium azide)

References

http://www.ncbi.nlm.nih.gov/pubmed/11187898
http://www.ncbi.nlm.nih.gov/pubmed/12668592