PRKDC monoclonal antibody, clone 18-2

Product Code: MAB3430

Code	Size	Price

MAB3430-100ug

100 ug

£1,271.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Mouse

Antibody Isotype: 2 IgG1

Antibody Clonality: Monoclonal

Antibody Clone: 18-Feb

Regulatory Status: RUO

Target Species: Human

Applications:

Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)

Storage:

Store at 4°C.

Documents

Supplier External Link

Further Information

Antigen Target Species:

Human

Form:

Liquid

Gene Alias:

Gene Description:

protein kinase, DNA-activated, catalytic polypeptide

Gene ID:

5591

Gene Name:

PRKDC

Immunogen:

Native purified PRKDC from HeLa cells.

Note:

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Product Description:

Mouse monoclonal antibody raised against native PRKDC.

Recommend Dilutions:

Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.

Specificity:

Reacts with the 460 KDa catalytic subunit of DNA-dependent Protein Kinase (DNA-PKcs). Inhibits kinase activity of DNA-PKcs ~50%, but preincubation of enzyme with DNA protects DNA-PKcs from inactivation by clone 18-2. In Western blot, clone 18-2 reacts with intact DNA-PKcs as well as its degradation products.

Storage Buffer:

In 10 mM PBS, pH 7.4 (0.09% sodium azide)