CTNNB1 monoclonal antibody, clone BDI480
| Code | Size | Price |
|---|
| MAB3925-100ug | 100 ug | £933.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: BDI480
Regulatory Status: RUO
Applications:
- Enzyme Immunoassay (EIA)
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Aliquot to avoid repeated freezing and thawing.
Documents
Further Information
Form:
Lyophilized
Immunogen:
A synthetic peptide corresponding to CTNNB1.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against synthetic peptide of CTNNB1.
Recommend Dilutions:
ELISA (0.05 ug/mL)
Western Blot (0.5 ug/mL for HRP/ECL detection)
Immunocytochemistry (1-10 ug/mL)
The optimal working dilution should be determined by the end user.
Western Blot (0.5 ug/mL for HRP/ECL detection)
Immunocytochemistry (1-10 ug/mL)
The optimal working dilution should be determined by the end user.
Specificity:
Specifically interacts with beta-catenin. The alpha-, beta- and gamma-catenins are cytoplasmic proteins mediating the interaction of Ca2+ -dependent transmembrane adhesion molecules (cadherins) with the cytoskeletal network. The direct interaction of beta-catenin with the cytoplasmic domain of cadherins plays a crucial role for cell-cell adhesion and signal transmission between neighboring cells. Recent studies indicate that beta-catenin may also play a role in tumorigenesis since it forms complexes with the tumor suppressor gene product APC. Beta-catenin directly interacts and constitutively activates transcription factors of the TCF/LEF gene family. Thus it is proposed that beta-catenin plays a dual role not only in the maintenance and regulation of cell-cell interactions but also in the regulation of gene activity. Cross reacts with human, mouse and dog.
Storage Buffer:
Lyophilized from 2x PBS (PEG, sucrose, 0.09% sodium azide)