CD226 monoclonal antibody, clone DX11
| Code | Size | Price |
|---|
| MAB5270-100ug | 100 ug | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: 2 IgG1
Antibody Clonality: Monoclonal
Antibody Clone: DX11
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Immunoprecipitation (IP)
Storage:
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Aliquot to avoid repeated freezing and thawing.
Documents
Further Information
Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
DNAM-1|DNAM1|PTA1|TLiSA1
Gene Description:
CD226 molecule
Gene ID:
10666
Gene Name:
CD226
Immunogen:
Native purified CD226 from human cytotoxic T lymphocyte clone.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against native CD226.
Recommend Dilutions:
Flow Cytometry (10ul of the suggested working dilution (1:25-1:100) to label 1x 106 cells in 100ul)
The optimal working dilution should be determined by the end user.
The optimal working dilution should be determined by the end user.
Specificity:
This antibdoy recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells (3).
Storage Buffer:
In PBS, pH 7.4 (0.09% sodium azide)