Neurofilament monoclonal antibody, clone 403

Human

Liquid

Native purified human Neurofilament.

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Mouse monoclonal antibody raised against native Neurofilament.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10)
The optimal working dilution should be determined by the end user.

The monoclonal antibody reacts specific with the medium component of the three subunits of neurofilaments. In immunoblots it reacts with the 160 kD protein. Neurofilaments, the intermediate filaments of neurons, are composed of three polypeptides with a moleculeweight of respecitively, 70, 160 and 200 kD. The three polypeptides can be differentially expressed during neuronal development, or in adult brain tissue. Antibodies directed against the three different neurofilament proteins can be an important aid in studying neurofilament expression pattern and in testing of tumours.

In tissue culture supernatant (0.09% sodium azide)