anti-DLK1 (human), mAb (PF299-1)

AdipoGen Life Sciences
Product Code: AG-20A-0070
Product Group: Primary Antibodies
CodeSizePrice
AG-20A-0070-C05050 ug£189.00
Quantity:
AG-20A-0070-C100100 ug£260.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1κ
Antibody Clonality: Monoclonal
Antibody Clone: PF299-1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
-20°C

Images

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Immunohistochemical staining of DLK1 using anti-DLK1 (human), mAb (PF299-1) (Prod. No. AG-20A-0070) in placenta, villi (1:500 dilution). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for use

Immunohistochemical staining of DLK1 using anti-DLK1 (human), mAb (PF299-1) (Prod. No. AG-20A-0070) in placenta, villi (1:500 dilution). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for use

Further Information

Alternate Names/Synonyms:
Protein Delta Homolog 1; Fetal Antigen 1; Preadipocyte Factor 1; Pref-1; FA1
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human DLK1 (extracellular domain).
Long Description:
Monoclonal Antibody. Recognizes human DLK1. Does not cross-react with mouse DLK1. Isotype: Mouse IgG1kappa. Clone: PF299-1. Applications: ELISA, FACS, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
NCBI, Uniprot Number:
P80370
Package Type:
Plastic Vial
Product Description:
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
Specificity:
Recognizes human DLK1. Does not cross-react with mouse DLK1.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1: S.M. Kluth, et al.; Stem Cells Int. 2013, ID985285 (2013)