anti-FGF-23 (human), mAb (FG322-3)
| Code | Size | Price |
|---|
| AG-20A-0073-C050 | 50 ug | £184.00 |
Quantity:
| AG-20A-0073-C100 | 100 ug | £303.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1κ
Antibody Clonality: Monoclonal
Antibody Clone: FG322-3
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
-20°C
Further Information
Alternate Names/Synonyms:
Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human FGF-23.
Long Description:
Monoclonal Antibody. Recognizes human FGF-23. Does not cross-react with mouse FGF-23. Isotype: Mouse IgG1kappa. Clone: FG322-3. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
NCBI, Uniprot Number:
Q9GZV9
Package Type:
Plastic Vial
Product Description:
FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
Specificity:
Recognizes human FGF-23. Does not cross-react with mouse FGF-23.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.
References
Immunohistochemical and molecular detection of the expression of FGF23 in phosphaturic mesenchymal tumors including the non-phosphaturic variant: E. Shiba, et al.; Diagn. Pathol. 11, 26 (2016) | A case of hyperparathyroidism which developed after resection of a fibroblast growth factor 23-producing tumor: K. Koikawa, et al.; Intern Med. 59, 2523 (2020) | Tumorinduzierte Osteomalazie, verursacht durch ein FGF23-sezernierendes Myoperizytom: N.M. Bushart, et al.; Der Orthop?de 49, 1 (2020)
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