anti-NQO1 (human), mAb (Skiny-1)
| Code | Size | Price |
|---|
| AG-20A-0086-C050 | 50 ug | £108.00 |
Quantity:
| AG-20A-0086-C100 | 100 ug | £173.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2aκ
Antibody Clonality: Monoclonal
Antibody Clone: Skiny-1
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
-20°C
Further Information
Alternate Names/Synonyms:
NAD(P)H Dehydrogenase (Quinine) 1 (NQO1); Quinone Reductase 1 (QR1); DT-Diaphorase (DTD); Azoreductase; Phylloquinone Reductase; Menadione Reductase; Dioxin-inducible 1; Disphorase-4 (DIA4); NAD(P)H:Quinone Oxireductase; NAD(P)H:Quinone Oxidoreductase 1
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human NQO1.
Long Description:
Monoclonal Antibody. Recognizes human NQO1. Detects a band of ~32kDa by Western blot. Isotype: Mouse IgG2akappa. Clone: Skiny-1. Applications: ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body?s protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer?s disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
NCBI, Uniprot Number:
Q3B792
Package Type:
Plastic Vial
Product Description:
NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body?s protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer?s disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
Specificity:
Recognizes human NQO1. Detects a band of ~32kDa by Western blot.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.