AdipoGen Life Sciences

anti-TRB-3 (human) pAb

Product Code:
 
AG-25A-0059
Product Group:
 
Primary Antibodies
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
-20°C
Storage:
 
-20°C
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Western blot analysis of human tissue lysate using anti-TRB3 (human), pAb (Prod. No. AG-25A-0059) at 1:2,000 dilution. 1. Human spleen tissue lysate (10?g). 2. Human liver tissue lysate (10?g) 3. Human colon tissue lysate (10?g)
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Western blot analysis of human tissue lysate using anti-TRB3 (human), pAb (Prod. No. AG-25A-0059) at 1:2,000 dilution. 1. Human spleen tissue lysate (10?g). 2. Human liver tissue lysate (10?g) 3. Human colon tissue lysate (10?g)

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AG-25A-0059-C100100 ug£173.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Tribbles Homolog 3; Neuronal Cell death-inducible Putative Kinase; SINK; p65-interacting Inhibitor of NF-kappaB
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
Long Description:
Polyclonal Antibody. Recognizes human TRB-3. Detects a band of ~28kDa by Western blot (predicted 39kDa). Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
NCBI, Uniprot Number:
Q96RU7
Package Type:
Plastic Vial
Product Description:
Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
Source / Host:
Rabbit
Specificity:
Recognizes human TRB-3. Detects a band of ~28kDa by Western blot (predicted 39kDa).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.