anti-NMNAT2 (human) pAb

AdipoGen Life Sciences
Product Code: AG-25A-0113
Product Group: Primary Antibodies
CodeSizePrice
AG-25A-0113-C100100 ug£173.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Guinea Pig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
-20°C
Storage:
-20°C

Images

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Immunohistochemical staining of NMNAT2 using anti-NMNAT2 (human), pAb (Prod. No. AG-25A-0113) in human brain cortex tissue (15?g/ml). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for

Immunohistochemical staining of NMNAT2 using anti-NMNAT2 (human), pAb (Prod. No. AG-25A-0113) in human brain cortex tissue (15?g/ml). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for

Further Information

Alternate Names/Synonyms:
Nicotinamide Mononucleotide Adenylyltransferase 2; NMN Adenylyltransferase 2; NaMN Adenylyltransferase 2
Concentration:
1 mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human NMNAT2.
Long Description:
Polyclonal Antibody. Recognizes human NMNAT2. Detects a band of ~35kDa by Western blot. Not tested in other species. Source: Guinea pig. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer?s disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.
NCBI, Uniprot Number:
Q9BZQ4
Package Type:
Plastic Vial
Product Description:
NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer?s disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.
Source / Host:
Guinea pig
Specificity:
Recognizes human NMNAT2. Detects a band of ~35kDa by Western blot. Not tested in other species.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.