anti-SLP-2 pAb

AdipoGen Life Sciences
Product Code: AG-25B-0019
Product Group: Primary Antibodies
CodeSizePrice
AG-25B-0019-C100100 ug£305.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
-20°C
Storage:
-20°C

Images

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Endogenous SLP-2 is localized to the mitochondria (Immunocytochemical staining).  Endogenous SLP-2 (green) (up) and endogenous mitochondrial HSP70 (red) (middle) were detected in methanol fixed HeLa cells using anti-SLP-2, pAb (Prod. No. AG-20B-0019

Endogenous SLP-2 is localized to the mitochondria (Immunocytochemical staining).  Endogenous SLP-2 (green) (up) and endogenous mitochondrial HSP70 (red) (middle) were detected in methanol fixed HeLa cells using anti-SLP-2, pAb (Prod. No. AG-20B-0019

Further Information

Alternate Names/Synonyms:
Stomatin-like Protein 2; EPB72-like 2
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In PBS containing 0.02% sodium azide.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Synthetic peptide corresponding to aa 199-213 of mouse SLP-2.
Long Description:
Polyclonal Antibody. Recognizes human, mouse and rat SLP-2. Source: Rabbit. Applications: ICC, IP, WB. Liquid. In PBS containing 0.02% sodium azide. SLP-2 (stomatin-like protein 2) is an unusual stomatin homolog. IT is a mitochondrial protein and functions in energy process by MMP maintenance, and subsequently affecting cell motility, proliferation and chemosensitivity. SLP-2 was identified as a cancer-related gene overexpressed in human ESCC, lung cancer, laryngeal cancer, and endometrial adenocarcinoma. In tumor cells, SLP-2 promotes cell growth, cell adhesion, and tumorigenesis.
NCBI, Uniprot Number:
Q99JB2
Package Type:
Plastic Vial
Product Description:
SLP-2 (stomatin-like protein 2) is an unusual stomatin homolog. It is a mitochondrial protein and functions in energy process by MMP maintenance and subsequently affecting cell motility, proliferation and chemosensitivity. SLP-2 was identified as a cancer-related gene overexpressed in human ESCC, lung cancer, laryngeal cancer and endometrial adenocarcinoma. In tumor cells, SLP-2 promotes cell growth, cell adhesion and tumorigenesis.
Source / Host:
Rabbit
Specificity:
Recognizes human, mouse and rat SLP-2.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability: S. Da Cruz, et al.; Biochim. Biophys. Acta 1783, 904 (2008) | SLP-2 is required for stress-induced mitochondrial hyperfusion: D. Tondera, et al.; EMBO J. 28, 1589 (2009)