Bisindolylmaleimide II
Code | Size | Price |
---|
AG-CR1-0010-M001 | 1 mg | £60.00 |
Quantity:
AG-CR1-0010-M005 | 5 mg | £160.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Images
Documents
Further Information
Alternate Names/Synonyms:
BIM II
Appearance:
Orange solid.
CAS:
137592-45-1
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-14H2,1H3,(H,29,32,33)
InChiKey:
LBFDERUQORUFIN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 137592-45-1. Formula: C27H26N4O2. MW: 438.5. Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A (PKA).
MDL:
MFCD00236430
Molecular Formula:
C27H26N4O2
Molecular Weight:
438.5
Package Type:
Vial
Product Description:
Protein kinase C (PKC) inhibitor [1, 2]. Binds with reversed orientation to protein kinase A (PKA) [1].
Purity:
>97% (mixture of 2 isomers) (NMR)
SMILES:
CN1CCCC1CCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CNC2=C1C=CC=C2
Solubility Chemicals:
Soluble in DMSO or 100% ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991) | The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A: M. Gassel, et al.; J. Biol. Chem. 279, 23679 (2004)
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