Ketanserin . tartrate
| Code | Size | Price |
|---|
| AG-CR1-0014-M010 | 10 mg | £36.00 |
Quantity:
| AG-CR1-0014-M050 | 50 mg | £60.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
4°C
Documents
Further Information
Alternate Names/Synonyms:
3-[2-[4-(4-Fluorobenzoyl)-1-piperdinyl)ethyl]-2,4(1H,3H)-quinazolinedione tartrate
Appearance:
White to off-white solid.
CAS:
83846-83-7
Class:
6.1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Handling Advice:
Protect from moisture.
Hazards:
H301
InChi:
InChI=1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)
InChiKey:
KMTLTEVOQLMYRS-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 83846-83-7. Formula: C22H22FN3O3 . C4H6O6. MW: 395.4 . 150.1. Selective 5-HT2A serotonin receptor antagonist. ATP-sensitive potassium channel inhibitor. hERG potassium channel blocker.
MDL:
MFCD11864992
Molecular Formula:
C22H22FN3O3 . C4H6O6
Molecular Weight:
395.4 . 150.1
Package Type:
Vial
PG:
III
Precautions:
P270, P301, P310
Product Description:
Selective 5-HT2A serotonin receptor antagonist [1]. ATP-sensitive potassium channel inhibitor [2]. hERG potassium channel blocker [3].
Purity:
>98% (NMR)
Signal word:
Danger
SMILES:
[CH2]C#CC.OOOOOO.FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=O)NC3=CC=CC=C3C2=O)CC1
Solubility Chemicals:
Soluble in DMSO; slightly soluble in water (4 mg/ml) or 100% ethanol (3 mg/ml).
Transportation:
Excepted Quantity
UN Nummer:
UN 2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
Vascular activity of ketanserin (R 41 468), a selective 5-HT2 receptor antagonist: J.M. van Nueten, et al.; Arch. Int. Pharmacodyn. Ther. 250, 328 (1981) | Ketanserin, a 5-HT2 antagonist, directly inhibits the ATP-sensitive potassium channel in mouse ventricular myocytes: J.M. Ju, et al.; J. Cardiovasc. Pharmacol. 47, 96 (2006) | The 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-a-go-go-related gene (hERG) potassium channels: Q. Li, et al.; Br. J. Pharmacol. 155, 365 (2008)