Necrostatin-7
| Code | Size | Price |
|---|
| AG-CR1-0054-M005 | 5 mg | £80.00 |
Quantity:
| AG-CR1-0054-M025 | 25 mg | £255.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Nec-7
Appearance:
Yellow solid.
CAS:
351062-08-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H302
InChi:
InChI=1S/C16H10FN5OS2/c17-11-3-1-9(2-4-11)13-10(8-20-21-13)7-12-14(23)22(15(18)25-12)16-19-5-6-24-16/h1-8,18H,(H,20,21)/b12-7-,18-15?
InChiKey:
SMJGLNVGTJLIRV-KBEFMPHXSA-N
Long Description:
Chemical. CAS: 351062-08-3. Formula: C16H10FN5OS2. MW: 371.4. Necroptosis inhibitor. Does not inhibit RIP1 kinase.
MDL:
MFCD02334728
Molecular Formula:
C16H10FN5OS2
Molecular Weight:
371.4
Package Type:
Vial
Precautions:
P270, P301, P312, P330
Product Description:
Necroptosis inhibitor [1]. Does not inhibit RIP1 kinase [1].
Purity:
>98% (NMR)
Signal word:
Warning
SMILES:
FC1=CC=C(C=C1)C1=NNC=C1C=C1SC(=N)N(C1=O)C1=NC=CS1
Solubility Chemicals:
Soluble in DMSO or 100% ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7: W. Zheng, et al.; Bioorg. Med. Chem. Lett. 18, 4932 (2008)