MS-1020
| Code | Size | Price |
|---|
| AG-CR1-3501-M001 | 1 mg | £70.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide; 2-Naphthalenecarboxamide
Appearance:
White to off-white solid.
CAS:
1255516-86-9
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light.
InChi:
InChI=1S/C21H18N2O3/c24-15-6-8-19-18(11-15)14(12-23-19)9-10-22-21(26)17-7-5-13-3-1-2-4-16(13)20(17)25/h1-8,11-12,23-25H,9-10H2,(H,22,26)
InChiKey:
KHJNISGKGIHTMY-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1255516-86-9. Formula: C21H18N2O3. MW: 346.4. Selective JAK3 inhibitor. Blocks STAT signaling. Inducer of apoptosis via down-regulation of anti-apoptotic gene expression.
MDL:
MFCD21363377
Molecular Formula:
C21H18N2O3
Molecular Weight:
346.4
Package Type:
Vial
Product Description:
Selective JAK3 inhibitor [1]. Blocks STAT signaling [1]. Inducer of apoptosis via down-regulation of anti-apoptotic gene expression [1].
Purity:
>95% (NMR)
SMILES:
OC1=CC2=C(NC=C2CCNC(=O)C2=CC=C3C=CC=CC3=C2O)C=C1
Solubility Chemicals:
Soluble in DMSO (at least 5 mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
MS-1020 is a novel small molecule that selectively inhibits JAK3 activity: B.H. Kim, et al.; Br. J. Haematol. 148, 132 (2010)