Shz-1
| Code | Size | Price |
|---|
| AG-CR1-3502-M001 | 1 mg | £40.00 |
Quantity:
| AG-CR1-3502-M005 | 5 mg | £100.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Sulfonylhydrazone-1; 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid
Appearance:
White to yellow solid.
CAS:
326886-05-9
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light.
InChi:
InChI=1S/C13H11BrN2O3S/c14-11-6-7-13(17)10(8-11)9-15-16-20(18,19)12-4-2-1-3-5-12/h1-9,16-17H/b15-9+
InChiKey:
OEMCLQLAWYKPRK-OQLLNIDSSA-N
Long Description:
Chemical. CAS: 326886-05-9. Formula: C13H11BrN2O3S. MW: 355.2. Enhancer of myocardial regenerative repair by stem cells. Potent inducer of Nkx2.5 and a subset of other cardiac markers, including myocardin, and sarcomeric-tropomyosin (SalphaTM) in a variety of different stem/progenitor cells.
MDL:
MFCD00853265
Molecular Formula:
C13H11BrN2O3S
Molecular Weight:
355.2
Package Type:
Vial
Product Description:
Enhancer of myocardial regenerative repair by stem cells [1]. Potent inducer of Homeobox protein Nkx2.5 and a subset of other cardiac markers, including myocardin, and sarcomeric-tropomyosin (SalphaTM) in a variety of different stem/progenitor cells [1].
Purity:
>95% (NMR)
SMILES:
OC1=C(C=NNS(=O)(=O)C2=CC=CC=C2)C=C(Br)C=C1
Solubility Chemicals:
Soluble in DMSO (at least 5 mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Cardiogenic small molecules that enhance myocardial repair by stem cell: H. Sadek, et al.; PNAS 105, 6063 (2008) | Synthetic sulfonyl-hydrazone-1 positively regulates cardiomyogenic microRNA expression and cardiomyocyte differentiation of induced pluripotent stem cells: M. Quattrocelli, et al.; J. Cell Biochem. 112, 2006 (2011) | Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule: Ch. Nan, et al.; Cardiovasc. Toxicol. 15, 29 (2015)