CJ-21058
| Code | Size | Price |
|---|
| BVT-0064-M001 | 1 mg | £140.00 |
Quantity:
| BVT-0064-M005 | 5 mg | £425.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
(5R,Z)-3-(Hydroxy((1R,2S,6S,8aS)-1,3,6-trimethyl-2-((E)-prop-1-en-1-yl)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)methylene)-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
Appearance:
Off-white solid.
CAS:
405072-57-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light when in solution.
Hazards:
H302, H312, H319
InChi:
InChI=1S/C23H33NO4/c1-6-7-16-14(3)11-15-10-13(2)8-9-17(15)23(16,4)21(27)19-20(26)18(12-25)24(5)22(19)28/h6-7,11,13,15-18,25,27H,8-10,12H2,1-5H3/b7-6+,21-19-/t13-,15?,16-,17-,18+,23-/m0/s1
InChiKey:
ZTPMRDYXXHRMRU-YLTLMIQISA-N
Long Description:
Chemical. CAS: 405072-57-3. Formula: C23H33NO4. MW: 387.5. Isolated from Phoma sp. ?Antibiotic. SecA inhibitor. Antibacterial and antifungal. Cytotoxic. Methyl analog of equisetin.
Molecular Formula:
C23H33NO4
Molecular Weight:
387.5
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Antibiotic. SecA inhibitor. Antibacterial and antifungal. Cytotoxic. Methyl analog of equisetin.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
[H][C@]1(CO)N(C)C(=O)C(=C(/O)[C@@]2(C)[C@@H](C=CC)C(C)=CC3([H])C[C@@H](C)CC[C@]23[H])C1=O
Solubility Chemicals:
Soluble in methylene chloride, DMSO or methanol.
Source / Host:
Isolated from Phoma sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
CJ-21,058, a new SecA inhibitor isolated from a fungus Y. Sugie, et al. J. Antibiot. 55, 25 (2002) | Discovery of the first SecA inhibitors using structure-based virtual screening M. Li, et al. BBRC 386 839 (2008) | Post-translational import of protein into the endoplasmic reticulum of atrypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities B. Patham, et al. Biochem. J. 419, 507 (2009)
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