Bioviotica

Isatropolone A

Product Code:
 
BVT-0080
Supplier:
 
Bioviotica
Regulatory Status:
 
RUO
Shipping:
 
20°C
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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BVT-0080-M0011 mg£140.00
Quantity:
BVT-0080-M0055 mg£395.00
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This product comes from: Switzerland.
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Further Information

Appearance:
Orange powder.
Class:
6.1
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS06
Handling Advice:
Protect from light when in solution.
Hazards:
H300, H310, H319, H330, H351
InChi:
InChI=1S/C24H24O9/c1-5-6-13(25)16-11-7-9(2)31-20-15(11)12(18(16)27)8-14(26)17-21(20)33-23-24(17,29)22(28)19(30-4)10(3)32-23/h7-8,10,19,22-23,28-29H,5-6H2,1-4H3/t10-,19?,22-,23+,24-/m1/s1
InChiKey:
GPTONKSPQNETHU-DLIRKSNVSA-N
Long Description:
Chemical. Formula: C24H24O9. MW: 456.5. Isolated from Streptomyces rubiginosohelvolus Gö66. Cytostatic. Cytotoxic (3-10 µM).
Molecular Formula:
C24H24O9
Molecular Weight:
456.5
Package Type:
Plastic Vial
PG:
III
Precautions:
P201, P260, P262, P280, P301, P310, P302, P350, P310, P405
Product Description:
Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania. Amine-reactive fluorescent compound. Cytostatic. Weak cytotoxic (3-10 µM).
Purity:
>98% (HPLC)
Signal Word:
Danger
SMILES:
[H][C@]12OC3=C(C(=O)C=C4C(=O)C(C(=O)CCC)=C5C=C(C)OC3=C45)[C@@]1(O)[C@H](O)[C@H](OC)[C@@H](C)O2
Solubility Chemicals:
Soluble in DMSO, chloroform or dichloromethane.
Source / Host:
Isolated from Streptomyces rubiginosohelvolus G?66.
Transportation:
Excepted Quantity
UN Nummer:
UN 3462
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.

References

Isolierung, Strukturaufkl?rung und Biosynthese der Isatropolone aus Streptomyces sp. Gö66: N. Pöhlmann; PhD Thesis; Univ. Göttingen, Cuvillier Verlag, Page 1-136 (2004) [ISBN 3-86537-286-4] | Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from Streptomyces?Gö66: X. Cai, et al.; Angew. Chem. Int. Ed. Engl. 56, 4945 (2017)