Bacimethrin
| Code | Size | Price |
|---|
| BVT-0226-C500 | 500 ug | £150.00 |
Quantity:
| BVT-0226-M001 | 1 mg | £255.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
4-Amino-2-methoxy-5-pyrimidinemethanol; 4-Amino-5-hydroxymethyl-2-methoxypyrimidine
Appearance:
Off-white powder.
CAS:
08/12/3690
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H302, H312, H319
InChi:
InChI=1S/C6H9N3O2/c1-11-6-8-2-4(3-10)5(7)9-6/h2,10H,3H2,1H3,(H2,7,8,9)
InChiKey:
ZPNHGSNYBLXGOL-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 3690-12-8. Formula: C6H9N3O2. MW: 155.2. Isolated from Streptomyces albus. Derivative of 5-Hydoxymethylcytosine (Prod. No. BVT-0229). Antibiotic. Antibacterial. Thiamine antagonist. Phosphatase kinase inhibitor
MDL:
MFCD01689392
Molecular Formula:
C6H9N3O2
Molecular Weight:
155.2
Package Type:
Plastic Vial
Precautions:
P270, P280, P301, P312, P302, P352, P312
Product Description:
Derivative of 5-Hydoxymethylcytosine (Prod. No. BVT-0229). Antibiotic. Antibacterial. Thiamine antagonist. Phosphatase kinase inhibitor.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
COC1=NC(N)=C(CO)C=N1
Solubility Chemicals:
Soluble in DMSO (50mg/ml), methanol (15mg/ml) or water (10mg/ml).
Source / Host:
Isolated from Streptomyces albus.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
Biological studies on bacimethrin, a pyrimidine antibiotic, and monazomycin: T. Nishimura & N. Tanaka; J. Antibiot. 16, 179 (1963) | Bacimethrin isolated from Streptomyces albus identification, derivatives, synthesis and biological properties: H. Drautz, et al.; J. Antibiot. 40, 1431 (1987) | Nucleoside antibiotics: Structure, biological activity, and biosynthesis: K. Isono; J. Antibiot. 41, 1711 (1988) (Review) | The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite: J.J. Reddick, et al.; Bioorg. Med. Chem. Lett. 11, 2245 (2001) | Hydrophilic modifications in peptide nucleic acid - Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine: R.H.E. Hudson, et al.; Can. J. Chem. 85, 302 (2007) | Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin: N.S Nemeria, et al.; Biochemistry 55, 1135 (2016)
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