Antibiotic PF 1052
| Code | Size | Price |
|---|
| BVT-0338-C500 | 500 ug | £130.00 |
Quantity:
| BVT-0338-M001 | 1 mg | £215.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
(E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione
Appearance:
Light brown solid.
CAS:
147317-15-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light when in solution.
Hazards:
H302, H312, H319, H332
InChi:
InChI=1S/C26H39NO4/c1-8-14(3)22-24(29)21(25(30)27(22)7)23(28)20-18(26(6)16(5)31-26)10-9-17-12-13(2)11-15(4)19(17)20/h9-10,13-20,22,28H,8,11-12H2,1-7H3/b23-21+
InChiKey:
NPWKEUKXVOMELT-XTQSDGFTSA-N
Long Description:
Chemical. CAS: 147317-15-5. Formula: C26H39NO4. MW: 429.6. Isolated from Phoma sp. Antibiotic. Antibacterial, antifungal and phytotoxic.
Molecular Formula:
C26H39NO4
Molecular Weight:
429.6
Package Type:
Plastic Vial
Precautions:
P261, P270, P280, P301, P312, P302, P352, P312
Product Description:
Antibiotic. Antibacterial, antifungal and phytotoxic. Anti-inflammatory agent. Described as neutrophil migration inhibitor.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CCC(C)C1N(C)C(=O)C(=C(O)C2C(C=CC3CC(C)CC(C)C23)C2(C)OC2C)C1=O
Solubility Chemicals:
Soluble in DMSO, methanol, methylene chloride, or chloroform (all at 10mg/ml).
Source / Host:
Isolated from Phoma sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
References
New antibiotic substance PF1052 and its production: T. Sasaki, et al.; Patent JP04316578A (1992) | Spylidone, a novel inhibitor of lipid droplet accumulation in mouse macrophages produced by Phoma sp. FKI-1840.: N. Koyama et al.; J. Antibiot. 58, 338 (2005) | Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library: X. Wang, et al.; Dis. Model Mech. 7, 163 (2014) | Loss of cftr function leads to pancreatic destruction in larval zebrafish: A. Navis, et al.; Dev. Biol. 399, 237 (2015)
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