Bisindolylmaleimide IV [Ro 31-6233]
| Code | Size | Price |
|---|
| AG-CR1-0152-M001 | 1 mg | £60.00 |
Quantity:
| AG-CR1-0152-M005 | 5 mg | £160.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Ro 31-6233; Arcyriarubin A; BIM IV; 2,3-bis(1H-Indol-3-yl)maleimide
Appearance:
Red to orange solid.
CAS:
119139-23-0
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
InChiKey:
DQYBRTASHMYDJG-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 119139-23-0. Formula: C20H13N3O2. MW: 327.3. Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
MDL:
MFCD00236432
Molecular Formula:
C20H13N3O2
Molecular Weight:
327.3
Package Type:
Vial
Product Description:
Cell permeable protein kinase C (PKC) inhibitor [1-3]. Inhibits also protein kinase A (PKA) [1,2].
Purity:
>98% (NMR)
SMILES:
O=C1NC(=O)C(C2=CNC3=C2C=CC=C3)=C1C1=CNC2=C1C=CC=C2
Solubility Chemicals:
Soluble in DMSO, ethanol, methanol or dimethylformamide.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
References
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991) | Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992) | Muscarinic interactions of bisindolylmaleimide analogues: S. Lazareno, et al.; Eur. J. Pharmacol. 360, 281 (1998)
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