anti-CD357 [GITR] (human), mAb (ANC5E3) (Biotin)
Code | Size | Price |
---|
ANC-368-030-100ug | 100 ug | £332.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Mouse IgG3 kappa
Antibody Clonality: Monoclonal
Antibody Clone: ANC5E3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
BI
Storage:
+4°C
Further Information
Alternate Names/Synonyms:
GITR; Glucocorticoid-induced TNF Receptor; AITR; Activation-inducible TNF-related; Tumor Necrosis Factor Receptor Superfamily Member 18; TNFRSF18
EClass:
32160000
Form (Short):
liquid
Formulation:
50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
Recombinant human GITR, PHA stimulated human PBL.
Labels - Conjugates:
Biotin
Long Description:
Monoclonal Antibody. Isotype: Mouse IgG3kappa. Clone: ANC5E3. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.
Package Type:
Plastic Vial
Product Description:
Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibody Conjugates
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
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