anti-DLL4 (mouse) mAb (9A1.5)

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AdipoGen Life Sciences
Product Code: AG-20B-0054
Product Group: Primary Antibodies
CodeSizePrice
AG-20B-0054-C100100 ug£280.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunocytochemistry (ICC)
Shipping:
-20°C
Storage:
-20°C

Documents

Further Information

Alternate Names/Synonyms:
Delta-like Protein 4; Delta4
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant mouse DLL4:Fc.
Long Description:
Monoclonal Antibody. Recognizes mouse DLL4. Isotype: Rat IgG1kappa. Clone: 9A1.5. Applications: FACS, ICC. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
NCBI, Uniprot Number:
Q9JI71
Package Type:
Plastic Vial
Product Description:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Purity:
>95% (SDS-PAGE)
Source / Host:
Purified from concentrated hybridoma tissue culture supernatant.
Specificity:
Recognizes mouse DLL4.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Thymic Crosstalk Regulates Delta-Like 4 Expression on Cortical Epithelial Cells: E. Fiorini, et al.; J. Immunol. 181, 8199 (2008)