White Line Inducing Principle [WLIP]
Product Code: AG-CN2-0069
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0069-M001 | 1 mg | £105.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
WLIP
Appearance:
White solid.
CAS:
135096-89-8
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep cool and dry.Protect from light.
InChi:
InChi=1/C54H95N9O16/c1-13-15-16-17-18-19-34(66)25-41(67)55-36(22-28(3)4)47(71)56-35(20-21-42(68)69)46(70)63-45-33(12)79-54(78)44(32(11)14-2)62-51(75)40(27-65)60-48(72)37(23-29(5)6)57-50(74)39(26-64)59-49(73)38(24-30(7)8)58-52(76)43(31(9)10)61-53(45)77/h28-40,43-45,64-66H,13-27H2,1-12H3,(H,55,67)(H,56,71)(H,57,74)(H,58,76)(H,59,73)(H,60,72)(H,61,77)(H,62,75)(H,63,70)(H,68,69)/t32?,33-,34?,35-,36+,37+,38-,39-,40-,43-,44+,45-/m1/s1
InChiKey:
QYEWAEAWMXRMHB-WRNJRVSGBN
Long Description:
Chemical. CAS: 135096-89-8. Formula: C54H95N9O16. MW: 1126.4. Isolated from Pseudomonas sp. Lipodepsipeptide (LDP). Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease. Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores. Antimicrobial. Antibacterial. Antifungal.
MDL:
N/A
Molecular Formula:
C54H95N9O16
Molecular Weight:
1126.4
Package Type:
Vial
Product Description:
Lipodepsipeptide (LDP) [1]. Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease [1, 5]. Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores [2]. Antimicrobial. Antibacterial. Antifungal [2 - 4].
Purity:
>98%
SMILES:
CCCCCCCC(O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CO)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](NC1=O)C(C)C)C(C)CC
Solubility Chemicals:
Soluble in DMSO, ethanol or methanol.
Source / Host:
Isolated from Pseudomonas sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Structure of the white-line-inducing principle isolated from Pseudomonas reactans: F. Han, et al.; Acta Cryst. C 48, 1965 (1992) | WLIP and tolaasin I, lipodepsipeptides from Pseudomonas reactans and Pseudomonas tolaasii, permeabilise model membranes: M. Coraiola, et al.; Biochim. Biophys. Acta 1758, 1713 (2006) | Biological characterization of white line-inducing principle (WLIP) produced by Pseudomonas reactans NCPPB1311: P. Lo Cantore, et al.; Mol. Plant Microbe Interact. 19, 1113 (2006) | Bioactive and structural metabolites of pseudomonas and burkholderia species causal agents of cultivated mushrooms diseases: A. Andolfi, et al.; Perspect. Medicin. Chem. 2, 81 (2008) | Genetic and functional characterization of cyclic lipopeptide white-line-inducing principle (WLIP) production by rice rhizosphere isolate Pseudomonas putida RW10S2: H. Rokni-Zadeh, et al.; Appl. Environ. Microbiol. 78, 4826 (2012)